The Food and Drug Administration (FDA) is limiting the amount of acetaminophen that can be found in many prescription painkillers. Products such as Vicodin and Percocet have been linked to reports of severe liver damage mostly in patients who take more than one product at a time.
Over the next three years, the FDA will lower the amount of prescription acetaminophen to 325 mg per dose. Currently the limit is 750 mg. For now, these new regulations only affect prescription medications. But changes may be coming soon for over the counter medications as well. You should not take more than 4ooo mg of acetaminophen a day.